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Product Code : HSB-BFGF
Pakage Size : 10 mg/vial, 50 mg/vial, 100 mg/vial, 500 mg/vial, 1 mg/vial
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Shipping and Handling Charges are not included (approximately $300 to USA).
For 100 mg/vial, addition of 1.5 ml water to one vial will result in 5 mM Tris buffer (pH7.6) with 150 mM NaCl (one vial also contains 0.8 mg sodium hyaluronic acid as stabilizer).
For 1 mg/vial, addition of 2.2 ml water to one vial will result in 5 mM Tris buffer (pH7.6) with 150 mM NaCl (no sodium hyaluronic acid is added).

Product Information
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Source : E. coli
Molecular weight : 17 kDa with 154 amino acid residues
Identification: First five N-terminal amino acid sequence was identified as Ala-Ala-Gly-Ser-Ile
Appearance : White lyophilized powder
Purity : > 95% analyzed by SDS-PAGE
Endotoxin : < 1 EU/vial
Protein Content: Assayed by Lowry method using BSA as a standard
Potency: Confirmed by growth promotion of HUVEC and Balb/3T3 cells using NIBSC bFGF standard
Sterility : Filter sterilized through 0.2 ㎛ filter and lyophilized aseptically
Expiration : 1 year after the manufacturing date
(Sealed product is stable until expiration if kept refrigerated)

BFGF is an 18kDa protein and a signal factor between multi-functional cell which participate in regulation of basic celluar processes such as proliferation, differentiation and etc. for various cell including fibroblast. It is also an essential factor for optimal body condition. 23 Members of the FGF family have been identified all of which are structurally related signaling molecules.
Especially, It is known that FGF-1(aFGF) or FGF-2(bFGF) has a strong cell-division effect for mesoblast structure.

Application
- Duodenal ulcer treatment
- adult vitiligo treatment
- wound treatment
- spinal wound treatment
- cartilage or bone damage treatment
- skin cell preliferation effect

BFGF effect as cosmetic source
bFGF exists in a dermal layer ,while EGF stimulate a epidermal layer. It stimulates in-body cell and produces collagen which is a main conponent of skin elasticity. It strengthens skin lagament which is decreased by aging and improves the skin wrinkle and elasticity. When fibroblast reacts actively, collagen maintains for a long time in the dermis, it makes an more elastic and shiny skin. It is decreased with aging. Just by applying bFGF simply in the skin, it is penentrated in the epidermis and acts effectively for dermal trouble such as wrinkle, melasma, and skin sagging .